Daniela Drescher

Department of Chemistry
Humboldt-Universität zu Berlin
Brook-Taylor-Str. 2, room 3‘308
12489 Berlin-Adlershof
Phone +49 30 20 93 71 33 or +49 30 81 04 58 90
daniela.drescher[at]bam.de

Curriculum Vitae

Since 11/2009 PhD Dissertation work: "Raman Spectroscopy of Nanoparticle-influenced Cellular Systems"
2008 Diplom (Dipl.-Chem.), Humboldt-Universität zu Berlin
Diploma thesis: "Synthesis of Phosphonic acids as Potential Inhibitors of Acid Sphingomyelinase"
2003-2008 Studies in Chemistry at the Humboldt-Universität zu Berlin
2003 Abitur

Publications

Papers

  • Büchner, T.; Drescher, D.; Merk, V.; Traub, H.; Guttmann P.; Werner S.; Jakubowski, N.; Schneider G., Kneipp, J., Biomolecular environment, quantification, and intracellular interaction of multifunctional magnetic SERS nanoprobes. Analyst 2016, 141 (17), 5096-5106 Abstract
  • Mueller, L; Traub, H.; Jakubowski, N.; Drescher, D.; Baranov, V. I.; Kneipp, J., Trends in Single-cell analysis by use of ICP-MS. Analytical and Bioanalytical Chemistry 2014, 406, 6963-6977 Abstract
  • Büchner, T.; Drescher, D.; Traub, H.; Schrade, P.; Bachmann, S.; Jakubowski, N.; Kneipp, J., Relating surface-enhanced Raman scattering signals of cells to gold nanoparticle aggregation as determined by LA-ICP-MS micromapping. Analytical and Bioanalytical Chemistry 2014, 406 (27), 7003-7014 Abstract
  • D. Drescher*, I. Zeise*, H. Traub, P.Guttmann, S. Seifert, T. Büchner, N. Jakubowski, G. Schneider, J. Kneipp, In situ characterization of SiO2 nanoparticle biointeractions using BrightSilica.
    Advanced Functional Materials 2014, 24 (24), 3765-3775 Abstract
  • Hoffmann, K.; Behnke, T.; Drescher, D.; Kneipp, J.; Resch-Genger, U., Near-Infrared-Emitting Nanoparticles for Lifetime-Based Multiplexed Analysis and Imaging of Living Cell. ACS Nano 2013, 7 (8), 6674-6684 Abstract
  • Hornemann, A.; Drescher, D.; Flemig, S.; Kneipp, J., Intracellular SERS hybrid probes using BSA–reporter conjugates. Anal. Bioanal. Chem. 2013, 405 (19), 6209–6222 Abstract
  • Drescher, D.; Guttmann, P.; Buechner, T.; Werner, S.; Laube, G.; Hornemann, A.; Tarek, B.; Schneider, G.; Kneipp, J., Specific biomolecule corona is associated with ring-shaped organization of silver nanoparticles in cells. Nanoscale 2013, 5(19), 9193-9198 Abstract
  • Drescher, D.; Büchner, T.; McNaughton, D.; Kneipp, J., SERS reveals the specific interaction of silver and gold nanoparticles with hemoglobin and red blood cell components, Phys. Chem. Chem. Phys. 2013, 15, 5364-5373 Abstract, Cover
  • Drescher, D.;, Giesen, C.; Traub, H.; Panne, U.; Kneipp, J.; Jakubowski, N., Quantitative Imaging of Gold and Silver Nanoparticles in Single Eukaryotic Cells by Laser Ablation ICP-MS. Anal. Chem. 2012, 84 , 9684-9688 Abstract
  • Drescher, D.; Kneipp, J., Nanomaterials in complex biological systems: insights from Raman spectroscopy. Chem. Soc. Rev. 2012, 41 , 5780-5799 Abstract
  • Giesen C.; Larissa W.; Mairinger T.; Drescher D.; Kneipp J.; Roos P. H.; Panne U.; Jakubowski N., Iodine as an elemental marker for imaging of single cells and tissue sections by laser ablation inductively coupled plasma mass spectrometry. J. Anal. At. Spectrom. 2011, 26, 2160-2165 Abstract Cover
  • Hoffmann, K.; Behnke, T.; Drescher, D.; Kneipp, J.; Resch-Genger, U.; Lifetime-based Discrimination between Spectrally Matching vis and NIR Emitting Particle Labels and Probes, Proc. of SPIE 2011, 7905, 79051F-1 Abstract
  • Drescher, D.; Orts-Gil, G.; Laube, G.; Natte, K.; Veh, R. W.; Österle W.; Kneipp, J., Toxicity of amorphous silica nanoparticles on eukaryotic cell model is determined by particle agglomeration and serum protein adsorption effects. Anal. Bioanal. Chem. 2011, 400, 1367-1373 Abstract
  • Orts-Gil, G.; Natte, K.; Drescher, D.; Bresch, H.; Mantion, A.; Kneipp, J.; Österle, W.; Characterisation of silica nanoparticles prior to in vitro studies: from primary particles to agglomerates. Journal of Nanoparticle Research 2011, 13, 1593-1604 Abstract
  • Matschulat, A.; Drescher, D.; Kneipp, J., Surface-Enhanced Raman Scattering Hybrid Nanoprobe Multiplexing and Imaging in Biological Systems. ACS Nano 2010, 4, 3259-3269 Abstract
  • Roth, A. G.; Drescher, D.; Yang, Y.; Redmer, S.; Uhlig, S.; Arenz, C.; Potente und selektive Inhibition der sauren Sphingomyelinase durch Bisphosphonate, Angew. Chem. 2009, 76977700. / Potent and Selective Inhibition of Acid Sphingomyelinase by Bisphosphonates, Angew. Chem. Int. Ed. 2009, 75607563 Abstract

Posters/Talks

  • D. Drescher, P. Guttmann, T. Büchner, I. Zeise,  H. Traub, N. Jakubowski, G. Schneider, J. Kneipp, Combining nanoscale cryo X-ray tomography with SERS and laser ablation ICP-MS for the investigation of nanoparticle-cell interactions. HZB User Meeting, Berlin, Dezember 2013 (Abstract & Poster)
  • D. Drescher, H. Traub, P. Guttmann, T. Büchner, G. Schneider, N. Jakubowski, J. Kneipp,Investigation of nanoparticle-cell interactions by combining SERS with laser ablation ICP‑MS and 3D X-ray tomography. Workshop FT-IR Spectroscopy in Microbiological and Medical Diagnostics, Berlin, Oktober 2013(Abstract & Poster)
  • D. Drescher, P. Guttmann, I. Zeise, T. Büchner, G. Schneider, J. Kneipp, Combining SERS and 3D X-ray tomography to study nanoparticle-cell interactions. SAVVY Workshop, San Sebastián/Spain, August 2013 (Abstract & Talk)
  • D. Drescher, G. Laube, P. Guttmann, G. Schneider, J. Kneipp, Combination of SERS and advanced microscopic methods for the investigation of protein-particle-cell interactions. Workshop FT-IR Spectroscopy in Microbiological and Medical Diagnostics, Berlin, Germany Oktober 2011 (Abstract & Poster)
  • D. Drescher, G. Laube, P. Guttmann, G. Schneider, J. Kneipp, Silver nanoparticles in cultured cells as viewed from a combined SERS, bioassay, and ultrastructural approach. CellNanoSpec, Porquerolles/France, September 2011 (Abstract & Talk)
  • D. Drescher, G. Orts-Gil, G. Laube, K. Natte, R. W. Veh, W. Österle, J. Kneipp, Combining SERS and viability tests for the investigation of nanotoxicity. ECSBM, Coimbra, August 2011 (Abstract & Poster)
  • D. Drescher, A. Matschulat, J. Kneipp, Biological multiplex applications of optical nanoprobes in live cells. Tag der Chemie, Berlin, Juli 2011 (Abstract & Poster/Talk)
  • D. Drescher, A. Matschulat, J. Kneipp, Biological multiplex applications of optical nanoprobes in live cells. Symposium "Molecular Plasmonics", Jena, Mai 2011 (Abstract & Poster)
  • D. Drescher, G. Orts-Gil, W. Österle, J. Kneipp, Investigation of cytotoxicity of silica nanoparticles using viability tests and surface-enhanced Raman spectroscopy. Berliner Chemie Symposium, Berlin, April 2011 (Abstract & Poster)
  • D. Drescher, G. Orts-Gil, W. Österle, J. Kneipp, Investigation of cytotoxicity of silica nanoparticles using viability tests and surface-enhanced Raman spectroscopy. NanoBio Conference International, Zürich, August 2010 (Abstract & Poster)
  • D. Drescher, A. Matschulat, G. Orts-Gil, J. Kneipp, Combined intracellular SERS and cytotoxicity studies after uptake of silica nanoparticles. Analytica Conference, München, März 2010 (Abstract & Poster)
  • D. Drescher, A. Matschulat, J. Kneipp, Raman spectroscopy on nanoparticle-influenced cellular systems. BMBF-Nachwuchsförderung in der Biotechnologie, Berlin, Januar 2010 (Abstract & Poster)
  • D. Drescher, A. Matschulat, G. Orts Gil, J. Kneipp, Combined intracellular SERS and cytotoxicity studies after uptake of silica nanoparticles. RKI-Workshop "FT-IR Spectroscopy in Microbiological and Medical Diagnostics", Berlin, Oktober 2009 (Abstract & Poster)
  • D. Drescher, A. Matschulat, K. Hoffmann, J. Kneipp, Raman spectroscopy on nanoparticle-influenced cellular systems. Jubiläumssymposium 100 Jahre Adlershof "Licht – Materialien - Modelle", Berlin, September 2009 (Abstract & Poster)

Book chapter

  • Kneipp, J.; Drescher, D., SERS in Cells: from Concepts to Practical Applications. In: Ozaki, Y.; Kneipp, K.; Aroca, R. (eds.), Frontiers of Surface-Enhanced Raman Scattering: Single Nanoparticles and Single Cells. Wiley-VCH, 2014

* Contributed equally to the work